Saeko had long, waist-length dark brown hair and dark brown eyes. She had only been seen nearly naked in one scene. Later, in a photo, she is displayed in a typical summer dress and hat and a pair of sandals with her hair cut short at her shoulders.
Saeko worked at the college's medical school and was apparently renowned around campus for her accomplishments. She had been pregnant with her first child, Mana, fathered by Kurosu, who she gets married to and moves to Oshima with him to be with her family. Five years after having Mana, she became pregnant with Shu. While she was with her 5-year-old daughter, Mana, she (speculatively) and Mana came in contact with the meteorite that Mana found, and speculatively, the virus within the meteorite infected Saeko. Despite her infliction, she managed to carry Shu to term and her life was sacrificed in order for him to be born.
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|Main Characters | Ouma Shu | Yuzuriha Inori | Tsutsugami Gai|
|Organizations | Funeral Parlor | GHQ | Anti-Bodies | Sephira Genomics | Tennoz High|
|Tennoz High Students | Arisa Kuhouin | Hare Menjou | Souta Tamadate | Yahiro Samukawa | Kanon Kusama | Hirohide Nanba|
|Funeral Parlor Members | Ayase Shinomiya | Tsugumi | Fyu-Neru | Argo Tsukishima | Oogumo | Shibungi | Kyo | Kenji Kido|
|GHQ Members | Shuichiro Keido | Daryl Yan | General Yan | Segai Waltz Makoto | Guin | Dan Eagleman | Rowan | Emily | Haruka Ouma|
|Others | Mana Ouma | Kurosu Ouma | Saeko Shijou | Okina Kuhouin | Jun Samukawa | Yuu | Kurachi | Scrooge | Carol | Present | Past | Yet To Come | Overdose | Untreated|