|Air Date||November 18, 2011|
|Opening Song||My Dearest|
Cage:Leukocytes is the sixth episode of the Guilty Crown anime. It first aired on November 18, 2011.
Gai survives the attack, but says that his team and the mercenaries were killed by the Leukocyte blast. At the outskirts of Tsukigase Dam, Gai briefs Funeral Parlor that their mission is to attack the Dam where the Leukocyte control system is located, but due to the Leukocyte's security system, Shu will have to use Kenji's Void to disable it. Shu refuses to take part in the operation, as he's afraid that people will die if he fails, until Inori goes to talk to him. Meanwhile, at Tsukigase Dam, Major Seiga informs the Anti Bodies director Shuichiro Keido that his men are prepared for Funeral Parlor's attack; Daryl especially wants revenge for the theft of his Steiner.
As Gai gets another blood transfusion, he confesses to who he assumes is Inori that he regrets the deaths of those who sacrificed themselves for him and it was difficult to act as their fearless leader. When Inori arrives in his room, Gai realizes he was talking to Shu; Shu says that he never wanted to see this side of Gai and agrees to join the operation. As Funeral Parlor distracts the GHQ forces guarding the Dam, Shu, Gai, and Kenji sneak into the Leukocyte control system as Inori defends them.
As Gai and Shu hack the control system with Tsugumi's help via Funell, Seiga sends Daryl to stop them. Gai battles and disables Daryl's Endlave, but Daryl damages the control system, sending one of the Leukocytes crashing toward the Dam. In order to stop it, Gai makes a deal with Seiga that he will stop the crashing satellite using Shu's transmitter pen, revealing that it is actually a targeting beacon for the Leukocytes, if Seiga destroys all records of Shu's involvement with Funeral Parlor. Realizing that Gai is sacrificing himself to destroy the falling satellite, Shu, with Inori's encouragement, combines Kenji's and Inori's Voids to destroy not only the falling satellite but also the one still in space.
With the operation over, Shu finally accepts alliance with Gai and Funeral Parlor while Shuichiro speaks with a mysterious person about "Cocytus awakening."